Privacy is a controversial and important issue in scientific research. The patient or a healthy participant must be guaranteed that his or her data will not be made public. This issue is becoming increasingly important as a result of the technological developments in ‘big data'. This subproject implements procedures and technologies for privacy and security aspects in accordance with the guidelines specified in HANDS. This may include for instance the pseudonymisation of personal data via Trusted Third Parties, the encryption of citizen service numbers, and implementation of security standards.